Spruce Biosciences Inc (SPRB)

Currency in USD
83.7400
+0.9200(+1.11%)
Closed·
81.3400-2.4000(-2.87%)
·
SPRB is not included in our AI-picked strategies. See which stocks are.
Fair Value
Day's Range
82.950087.1100
52 wk Range
4.2750240.0000
Key Statistics
Prev. Close
83.74
Open
84.35
Day's Range
82.95-87.11
52 wk Range
4.275-240
Volume
36.53K
Average Volume (3m)
565.79K
1-Year Change
195.77%
Book Value / Share
9.57
Fair Value
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Fair Value Upside
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SPRB Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
230.5000
Upside
+175.26%
Members' Sentiments
Bearish
Bullish
ProTips
Stock generally trades with high price volatility

Spruce Biosciences Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Neutral
Technical Indicators
Strong Buy
Moving Averages
Sell

Spruce Company Profile

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure, and SPR204, a monoclonal antibody antagonist for Post-Bariatric Hypoglycemia. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize Tildacerfont for the treatment of CAH in Japan. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in South San Francisco, California.

Spruce Biosciences Inc SWOT Analysis


Tildacerfont Trials
Spruce Biosciences' future hinges on pivotal CAHmelia-204 and CAHptain-205 trials for tildacerfont, with results expected in Q4 2024
Market Dynamics
Explore the competitive landscape of CAH treatment, with Spruce facing challenges from Neurocrine Biosciences' crinecerfont in a market of 20,000-30,000 US patients
Financial Health
With $70M cash runway through 2025, Spruce Biosciences navigates critical development phases while exploring strategic alternatives to maximize shareholder value
Analyst Outlook
Price targets range from $1.50 to $3.00, reflecting varied perspectives on Spruce's potential in CAH treatment and expansion into Major Depressive Disorde
Read full SWOT analysis

Compare SPRB to Peers and Sector

Metrics to compare
SPRB
Peers
Sector
Relationship
P/E Ratio
−1.9x−4.9x−0.6x
PEG Ratio
0.130.130.00
Price/Book
16.6x7.8x2.6x
Price / LTM Sales
128.6x43.0x3.2x
Upside (Analyst Target)
165.6%52.6%41.8%
Fair Value Upside
Unlock−8.9%5.1%Unlock

Analyst Ratings

4 Buy
0 Hold
0 Sell
Ratings:
4 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 230.5000
(+175.26% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Oppenheimer
Buy283.00+237.95%-New Coverage23/12/2025
H.C. Wainwright
Buy220.00+162.72%-New Coverage22/12/2025
Leerink Partners
Buy160.00+91.07%-Upgrade03/12/2025
Citizens
Hold259.00+209.29%254.00Maintain11/11/2025
Citizens
Buy254.00+203.32%-Upgrade28/10/2025

Earnings

Latest Release
Nov 10, 2025
EPS / Forecast
-14.58 / -0.215
Revenue / Forecast
-- / 250.00K
EPS Revisions
Last 90 days

Spruce (SPRB) Income Statement & Profits

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FAQ

What Is the Spruce (SPRB) Share Price Today?

The live Spruce share price today is 83.7400

What Stock Exchange Does Spruce (SPRB) Trade On?

Spruce is listed and trades on the Nasdaq Stock Exchange.

What Is the Ticker (Stock Symbol) for Spruce?

The stock symbol (also called a 'ticker') for Spruce is "SPRB."

What Is the Current Spruce Market Cap?

As of today, Spruce market capitalisation is 89.63M.

What Is Spruce's (SPRB) Earnings Per Share (TTM)?

The Spruce EPS is currently -82.48 (Trailing Twelve Months).

When Is the Next Spruce Earnings Date?

Spruce's next earnings report will be released on 17 Nov 2025.

Is SPRB a Buy or Sell From a Technical Analyst Perspective?

Based on today's Spruce moving averages and other technical indicators, the daily buy/sell signal is Neutral.

How Many Times Has Spruce Stock Split?

Spruce has split 1 times. (See the SPRB stock split history page for full effective split date and price information.)

How Many Employees Does Spruce Have?

Spruce has 9 employees.

What is the current trading status of Spruce (SPRB)?

As of 24 Dec 2025, Spruce (SPRB) is trading at a price of 83.7400, with a previous close of 83.7400. The stock has fluctuated within a day range of 82.9500 to 87.1100, while its 52-week range spans from 4.2750 to 240.0000.

What Is Spruce (SPRB) Price Target According to Analysts?

The average 12-month price target for Spruce is USD230.5, with a high estimate of USD283 and a low estimate of USD160. 4 analysts recommend buying the stock, while 0 suggest selling, leading to an overall rating of Strong Buy. The stock has an +175.26% Upside potential.

What Is the SPRB After Hours Price?

SPRB's last after hours stock price is 81.3400, the stock has decreased by -2.4000, or -2.8700%.
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