Spero Therapeutics Inc (SPRO)

Currency in USD
2.330
-0.040(-1.69%)
Closed·
2.420+0.090(+3.86%)
·
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Fair Value
Day's Range
2.3102.415
52 wk Range
0.5053.220
Key Statistics
Prev. Close
2.37
Open
2.36
Day's Range
2.31-2.415
52 wk Range
0.505-3.22
Volume
245.25K
Average Volume (3m)
633.22K
1-Year Change
152.49%
Book Value / Share
0.47
Fair Value
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Fair Value Upside
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SPRO Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
4.000
Upside
+71.67%
Members' Sentiments
Bearish
Bullish
ProTips
Analysts anticipate sales decline in the current year

Spero Therapeutics Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Sell

Spero Therapeutics Company Profile

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company’s product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which is in Phase 3 development; and SPR720, a novel product candidate for first-line treatment of nontuberculous mycobacterial (NTM) pulmonary disease. It has license agreement with Meiji Seika Pharma Co., Ltd. to support the development of tebipenem HBr; Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries; and Vertex Pharmaceuticals Incorporated for patents relating to the oral prodrug SPR720, as well as SPR719, an active metabolite. Spero Therapeutics, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

Spero Therapeutics Inc Earnings Call Summary for Q2/2025

  • Q2 2025 EPS of -$0.03 beat -$0.57 forecast; revenue of $14.2M exceeded $11M estimate. Stock rose 7.27% post-earnings.
  • Successful Phase 3 trial for tebipenem HBr positions company for growth in antibiotic treatment market, FDA approval expected 2026.
  • Extended cash runway to 2028, supported by GSK partnership milestone payments. R&D expenses halved to $10.7M.
  • Challenges remain with SPR720 program; management exploring next steps. Analysts maintain 'Hold' with $5 price target.
  • CEO emphasized tebipenem HBr as potential first commercial product from pipeline, highlighting strategic focus on regulatory approval.
Last Updated: 12/08/2025, 22:10
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Compare SPRO to Peers and Sector

Metrics to compare
SPRO
Peers
Sector
Relationship
P/E Ratio
−3.0x−2.4x−0.6x
PEG Ratio
0.00−0.140.00
Price/Book
5.0x2.7x2.6x
Price / LTM Sales
3.2x376.4x3.2x
Upside (Analyst Target)
71.7%140.7%41.8%
Fair Value Upside
Unlock−10.2%5.1%Unlock

Analyst Ratings

0 Buy
1 Hold
0 Sell
Ratings:
1 analysts
Overall Consensus
Neutral

Analysts 12-Month Price Target:

Average 4.000
(+71.67% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate

Earnings

Latest Release
Nov 13, 2025
EPS / Forecast
-0.13 / -0.39
Revenue / Forecast
5.40M / 12.00M
EPS Revisions
Last 90 days

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FAQ

What Is the Spero Therapeutics (SPRO) Share Price Today?

The live Spero Therapeutics share price today is 2.330

What Stock Exchange Does Spero Therapeutics (SPRO) Trade On?

Spero Therapeutics is listed and trades on the Nasdaq Stock Exchange.

What Is the Ticker (Stock Symbol) for Spero Therapeutics?

The stock symbol (also called a 'ticker') for Spero Therapeutics is "SPRO."

What Is the Current Spero Therapeutics Market Cap?

As of today, Spero Therapeutics market capitalisation is 131.27M.

What Is Spero Therapeutics's (SPRO) Earnings Per Share (TTM)?

The Spero Therapeutics EPS is currently -0.79 (Trailing Twelve Months).

When Is the Next Spero Therapeutics Earnings Date?

Spero Therapeutics's next earnings report will be released on 26 Mar 2026.

Is SPRO a Buy or Sell From a Technical Analyst Perspective?

Based on today's Spero Therapeutics moving averages and other technical indicators, the daily buy/sell signal is Strong Buy.

How Many Times Has Spero Therapeutics Stock Split?

Spero Therapeutics has split 0 times. (See the SPRO stock split history page for full effective split date and price information.)

How Many Employees Does Spero Therapeutics Have?

Spero Therapeutics has 32 employees.

What is the current trading status of Spero Therapeutics (SPRO)?

As of 24 Dec 2025, Spero Therapeutics (SPRO) is trading at a price of 2.330, with a previous close of 2.370. The stock has fluctuated within a day range of 2.310 to 2.415, while its 52-week range spans from 0.505 to 3.220.

What Is Spero Therapeutics (SPRO) Price Target According to Analysts?

The average 12-month price target for Spero Therapeutics is USD4, with a high estimate of USD4 and a low estimate of USD4. 0 analysts recommend buying the stock, while 0 suggest selling, leading to an overall rating of Neutral. The stock has an +71.67% Upside potential.

What Is the SPRO Premarket Price?

SPRO's last pre-market stock price is 2.380. The pre-market share volume is 4,830.000, and the stock has decreased by 0.010, or 0.420%.

What Is the SPRO After Hours Price?

SPRO's last after hours stock price is 2.420, the stock has decreased by 0.090, or 3.860%.
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