Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 injection to treat duchenne muscular dystrophy (duchenne) in patients with confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping; AMONDYS 45 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene; and ELEVIDYS, an adeno-associated virus based gene therapy for the treatment of ambulatory pediatric patients aged 4 through 5 years with duchenne with a confirmed mutation in the duchenne gene. The company is also developing SRP-5051, a peptide conjugated PMO that binds exon 51 of dystrophin pre-mRNA; and SRP-9003, a limb-girdle muscular dystrophies gene therapy program. It has collaboration and license agreements with F. Hoffman-La Roche Ltd; Nationwide Children’s Hospital; Genevant Sciences; University of Florida; Dyno Therapeutics; Hansa Biopharma; Duke University; Genethon; and StrideBio. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.
DMD Market Leade | Sarepta Therapeutics dominates the Duchenne muscular dystrophy market with Elevidys, its groundbreaking gene therapy now approved for patients 6 and olde |
Financial Momentum | Q3 2024 revenue surpassed expectations at $430 million, driven by Elevidys' success. Analysts project peak U.S. sales of $2.7 billion for the therapy |
Strategic Pivot | Explore Sarepta's shift towards promising Limb-Girdle gene therapies, with regulatory filings expected in 2025, following PPMO franchise discontinuation |
Analyst Optimism | Discover why analysts maintain bullish outlooks, with price targets ranging from $167 to $209, reflecting confidence in Sarepta's growth potential |
Metrics to compare | SRPT | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipSRPTPeersSector | |
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P/E Ratio | 100.3x | −5.7x | −0.7x | |
PEG Ratio | 0.87 | −0.14 | 0.00 | |
Price/Book | 10.0x | 2.1x | 2.6x | |
Price / LTM Sales | 7.5x | 19.7x | 3.2x | |
Upside (Analyst Target) | 51.8% | 44.6% | 44.1% | |
Fair Value Upside | Unlock | 8.4% | 8.2% | Unlock |