Tvardi Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of novel, oral, and small molecule therapies targeting STAT3 to treat fibrosis-driven diseases with significant unmet need in the United States. The company's lead product candidates include TTI-101, which is in Phase 2 clinical development stage for fibrosis-driven diseases with an initial focus on idiopathic pulmonary fibrosis (IPF), and hepatocellular carcinoma (HCC); and TTI-109, an oral, small molecule STAT3 inhibitor which is in pre-clinical stage. Tvardi Therapeutics, Inc. was founded in 2017 and is based in Sugar Land, Texas.
Strategic Pivot | Cara Therapeutics refocuses on oral difelikefalin for notalgia paresthetica, streamlining operations amidst challenges with Korsuva commercialization |
Financial Outlook | Despite Q1 2024 losses, Cara projects cash reserves to fund operations into 2026, aligning with crucial KOURAGE Phase III study results timeline |
KOURAGE Trial Impact | Upcoming Part A results of KOURAGE Phase 3 trial viewed as critical inflection point, with potential to significantly boost investor confidence |
Market Potential | Analysts project peak sales of $630M by 2035 for oral DFK in notalgia paresthetica, with price targets ranging from $1 to $10 per share |
Metrics to compare | TVRD | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipTVRDPeersSector | |
|---|---|---|---|---|
P/E Ratio | −1.6x | −5.8x | −0.6x | |
PEG Ratio | −0.03 | −0.01 | 0.00 | |
Price/Book | 1.3x | 1.4x | 2.6x | |
Price / LTM Sales | - | 7.7x | 3.2x | |
Upside (Analyst Target) | 101.0% | 78.8% | 41.8% | |
Fair Value Upside | Unlock | 21.5% | 5.1% | Unlock |