Scholar Rock Holding Corporation, a biopharmaceutical company, focuses on the discovery, development, and delivery of medicines for the treatment of serious diseases in which signaling by protein growth factors plays a fundamental role. Its transforming growth factor beta (TGFß) superfamily biology, its novel understanding of the molecular mechanisms of growth factor activation enabled us to develop a proprietary platform for development of monoclonal antibodies that locally and selectively target the precursor. The company develops Apitegromab, an inhibitor of the activation of myostatin that is in Phase 3 clinical trial for the treatment of spinal muscular atrophy; and SRK-181, which has completed Phase 1 clinical trials for the treatment of cancers that are resistant to checkpoint inhibitor therapies, such as anti-PD-1 or anti-PD-L1 antibody therapies. It is developing a pipeline of product candidates to deliver novel therapies to treat a range of serious diseases, including neuromuscular disorders, cardiometabolic disorders, cancer, fibrosis, and iron-restricted anemia. Scholar Rock Holding Corporation was founded in 2012 and is headquartered in Cambridge, Massachusetts.
Pivotal Trial Awaits | Scholar Rock's SAPPHIRE trial for apitegromab in SMA nears completion, with potential to revolutionize treatment and drive significant market valuation |
Oncology Breakthrough | SRK-181 shows promise in overcoming resistance to immune checkpoint inhibitors, addressing a critical challenge in cancer treatment |
Expanding Horizons | Scholar Rock ventures into the lucrative obesity market with EMBRAZE trial and SRK-439, diversifying its pipeline beyond core focus areas |
Financial Outlook | Analyst targets range from $29 to $31, with potential for significant upside if pivotal trials succeed, despite current lack of revenue-generating assets |
Metrics to compare | SRRK | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipSRRKPeersSector | |
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P/E Ratio | −14.8x | −1.5x | −0.5x | |
PEG Ratio | 0.70 | −0.02 | 0.00 | |
Price/Book | 12.5x | 0.6x | 2.6x | |
Price / LTM Sales | - | 65.9x | 3.2x | |
Upside (Analyst Target) | 21.5% | 215.5% | 45.4% | |
Fair Value Upside | Unlock | 12.2% | 6.7% | Unlock |