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Needham starts Tscan Therapeutics stock with Buy, cites T-cell therapy potential

EditorEmilio Ghigini
Published 13/05/2024, 12:46
TCRX
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On Monday, Needham initiated coverage on Tscan Therapeutics Inc (NASDAQ: TCRX) stock, giving a Buy rating and setting a price target of $11.00.

The firm highlighted the biotechnology company's potential to revolutionize the T-cell-based therapeutic landscape, which is currently dominated by treatments focusing on a limited range of cell-surface antigens, primarily in hematologic oncology (heme-onc).

TScan's technology is designed to target more than 90% of intracellular proteins, which could significantly expand the range of treatable conditions.

The company's platform is unique in its ability to identify novel peptide-HLA (pHLA) and T-cell receptor (TCR) pairs from patients who have responded to checkpoint inhibitors (CPIs). This capability is viewed as a key advantage over existing therapies.

The firm expressed optimism about TScan's lead programs, TSC-100 and TSC-101, especially in the setting of transplants. Early results from these programs were presented at the American Society of Hematology (ASH) meeting in 2023 and were considered promising. The anticipation of further developments in the second half of 2024 has been cited as a potential catalyst for value creation for the company.

Needham's positive outlook on Tscan Therapeutics is based on the company's innovative approach to addressing tumor heterogeneity and antigen loss by using multiple pHLA/TCR combinations.

This strategy could improve the effectiveness of cancer treatments and support TScan's growth in the biopharmaceutical industry. The $11 price target reflects the firm's confidence in the company's prospects and the anticipated advancements in its therapeutic programs.

InvestingPro Insights

As Tscan Therapeutics Inc (NASDAQ: TCRX) garners attention with Needham's initiation of coverage and a bullish Buy rating, InvestingPro data reveals a nuanced financial landscape. TCRX's market capitalization stands at a modest $441.69 million, indicative of its status as a smaller player in the biotech field. Despite a negative P/E ratio of -5.81, reflecting current unprofitability, the company has demonstrated impressive revenue growth, with a 55.52% increase over the last twelve months as of Q4 2023 and an even more striking quarterly surge of 132.99% in Q4 2023.

InvestingPro Tips suggest that potential investors should consider the company's significant revenue growth as a positive indicator of its potential, particularly in light of its innovative T-cell-based therapies. However, it's also important to be mindful of the negative gross profit margin and operating income margin, which underscore the challenges TCRX faces in achieving profitability. To gain a deeper understanding of TCRX's financial health and future prospects, investors can access additional tips on InvestingPro, where there are currently PRONEWS24 additional tips available. Using this coupon code, investors can also get an additional 10% off a yearly or biyearly Pro and Pro+ subscription.

With a fair value estimate from analysts at $10 and the InvestingPro fair value at $5.59, there's a range of expectations regarding the company's valuation. As of the latest data, TCRX's stock is trading at 85.04% of its 52-week high, with a previous close at $7.73. The next earnings date on May 13, 2024, is likely to provide further insights into the company's trajectory and whether it can sustain its impressive revenue growth trend.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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