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Mizuho maintains Outperform rating on Neumora Therapeutics shares

EditorTanya Mishra
Published 09/09/2024, 12:08
NMRA
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Mizuho Securities has reiterated its Outperform rating on Neumora Therapeutics (NASDAQ: NMRA) with a steady price target of $20.00.


The firm's positive outlook follows a recent meeting with Neumora's CEO Henry Gosebruch and Head of Investor Relations Helen Rubenstein.


The discussions centered on the company's progress and expectations, particularly regarding its lead asset, navacaprant, which is currently in pivotal Phase 3 KOASTAL 1-3 studies for major depressive disorder (MDD).


The conversations also touched upon the potential positive outcomes from the ongoing navacaprant studies. Mizuho's confidence in the drug's prospects remains high after the meeting. Navacaprant is a novel kappa opioid receptor antagonist (KORA) being evaluated for its efficacy in treating MDD, a condition that affects millions globally.


In addition to its MDD-focused drug, Neumora is also developing NMRA-511 for Alzheimer's disease-related agitation. NMRA-511 is a novel vasopressin 1a receptor (V1aR) antagonist, another promising compound in the company's pipeline. The meeting provided insights into the strategy and development status of this asset as well.


In other recent news, Neumora Therapeutics has seen significant developments in its clinical trials and projects. Mizuho Securities maintains an Outperform rating on Neumora Therapeutics, following a recent meeting with the company's top executives, where progress of the leading drug candidate, navacaprant, was discussed.


Navacaprant is currently in Phase 3 studies for the treatment of major depressive disorder (MDD) and the expectations for a positive outcome were a focal point of the discussion.


Simultaneously, Neumora initiated a Phase 2 study for navacaprant, focusing on its potential in treating depression associated with bipolar II disorder, with topline data anticipated in the second half of 2025.


RBC Capital also maintained its Outperform rating on Neumora, expressing optimism for the ongoing Phase III clinical trials of navacaprant. The firm's positive outlook is based on recent developments in similar medications, suggesting navacaprant could yield promising results.


InvestingPro Insights


As Neumora Therapeutics (NASDAQ:NMRA) continues to attract attention with its innovative pipeline, recent data from InvestingPro provides a deeper financial perspective on the company. With a market capitalization of approximately $1.67 billion, Neumora's financial health is underscored by its ability to hold more cash than debt, an aspect that offers a degree of resilience in its operational strategy. This is further supported by the fact that the company's liquid assets exceed its short-term obligations, indicating a comfortable liquidity position.


However, investors should note that analysts have revised their earnings downwards for the upcoming period, which may reflect in the company's stock price performance. The stock has experienced a significant decline over the last week, and with a negative P/E ratio of -5.56, it reflects market sentiment regarding its current profitability challenges. Analysts also do not anticipate the company will be profitable this year, which aligns with an adjusted P/E ratio of -7.64 for the last twelve months as of Q2 2024.


Despite these challenges, Mizuho Securities maintains an Outperform rating, with a price target of $20.00, which is notably higher than the current price of $10.46. This target also suggests a potential upside when compared to the InvestingPro fair value estimate of $10.08. For additional insights, there are more InvestingPro Tips available for NMRA, which could help investors make more informed decisions.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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