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Iterum secures patents for antibiotic combinations

EditorAhmed Abdulazez Abdulkadir
Published 02/08/2024, 13:24
ITRM
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DUBLIN – Iterum Therapeutics plc (NASDAQ:ITRM), a clinical-stage pharmaceutical company, has been granted a Notice of Allowance for two U.S. patents and a Canadian patent, related to its antibiotic candidate, oral sulopenem.

The U.S. patents pertain to the use of sulopenem etzadroxil with probenecid, and with probenecid and valproic acid, for treating specific infections. The Canadian patent covers a bilayer tablet comprising these compounds.

The U.S. Patent and Trademark Office (USPTO) has concluded substantive examination for the patents, which are set to expire on April 1, 2039, and March 11, 2041, respectively, absent any extensions. The Canadian Intellectual Property Office (CIPO) has also concluded its examination, with the Canadian patent set to expire on December 23, 2039, barring extensions.

Iterum's CEO, Corey Fishman, expressed satisfaction with the strengthening of the company's patent estate, which now extends to Canada. The U.S. patents include application numbers 18/065,400 and 17/198,335, while the Canadian patent application number is 3129337.

The granted patents are part of Iterum's broader patent portfolio, which includes pending applications in Europe and China, supported by a Written Opinion of the International Search Authority confirming the novelty and inventiveness of the oral sulopenem bilayer tablet composition.

Iterum Therapeutics focuses on developing antibiotics to combat multi-drug resistant pathogens in community and hospital settings. Its lead compound, sulopenem, has shown potent activity against various resistant bacteria.

In other recent news, Iterum Therapeutics has launched a rights offering for its shareholders and certain warrant holders, aiming to raise capital for its operations. The offering, set at a subscription price of $1.21 per unit, allows the purchase of units that include ordinary shares and warrants. Maxim (NASDAQ:MXIM) Group LLC is acting as the dealer-manager for this non-transferable offering.

Iterum Therapeutics has reported a decrease in operating expenses for the first quarter of 2024, down to $6.2 million from $8.5 million the previous year. The company's net loss on a U.S. GAAP basis improved to $7.1 million from a net loss of $9.9 million in the first quarter of 2023.

InvestingPro Insights

Iterum Therapeutics plc (NASDAQ:ITRM) has recently bolstered its patent portfolio, a strategic move that could enhance its market position. InvestingPro data provides a snapshot of the company's current financial health, which is crucial for investors monitoring Iterum's progress.

As of the latest available data, Iterum Therapeutics has a market capitalization of approximately $19.37 million. The company's financial metrics reveal significant challenges, with a negative P/E ratio of -0.46, suggesting that investors are concerned about the company's profitability prospects. This is further evidenced by a negative Price/Book ratio of -3.15, indicating that the market values the company at less than the net value of its assets.

InvestingPro Tips highlight critical considerations for potential investors. The company is quickly burning through cash and suffers from weak gross profit margins, which are important factors to consider when evaluating the company's long-term viability. Moreover, Iterum Therapeutics does not pay a dividend to shareholders, which may influence investment decisions for those seeking income-generating assets.

For those interested in a deeper dive into Iterum Therapeutics' financials and strategic outlook, InvestingPro offers additional tips on the company's performance and projections. There are currently six more InvestingPro Tips available, providing insights into aspects such as the company's debt levels, expected profitability, and stock price volatility. These tips can be accessed by visiting https://www.investing.com/pro/ITRM.

Investors should keep an eye on Iterum's upcoming earnings date on August 9, 2024, to assess the company's progress and future direction. With a fair value estimation at $1.3 USD according to InvestingPro, there is a notable discrepancy with analyst targets, which place fair value at $6.5 USD, suggesting differing views on the company's potential.

The recent patent allowances may provide Iterum Therapeutics with a competitive edge in the antibiotics market, but investors will need to weigh these developments against the company's financial metrics and market performance to make informed decisions.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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