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Evaxion reports breakthrough in gonorrhea vaccine research

Published 09/09/2024, 12:28
EVAX
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COPENHAGEN - Evaxion Biotech A/S (NASDAQ: EVAX), a clinical-stage company focused on AI-driven vaccine development, has reported promising pre-clinical results for its novel EVX-B2 mRNA vaccine candidate targeting gonorrhea. The data, presented at the 18th Vaccine Congress in Lisbon, Portugal, today, indicates that EVX-B2 effectively triggers an immune response that eliminates the gonorrhea bacteria.


This recent development marks a significant milestone for Evaxion, as it showcases the versatility of its AI-Immunology™ platform, which is capable of identifying vaccine antigens that are delivery modality agnostic. This means that the platform's identified antigens can be used across various vaccine types, including mRNA and protein-based vaccines.


The pre-clinical Proof-of-Concept (PoC) for the mRNA version of EVX-B2 was achieved in collaboration with Afrigen Biologics, a biotech start-up based in Cape Town, South Africa. Afrigen Biologics is recognized for its role in establishing the first WHO/MPP mRNA Vaccine Technology Transfer hub in South Africa, which aims to develop and manufacture mRNA vaccines locally.


Christian Kanstrup, CEO of Evaxion, expressed excitement about reaching another milestone for 2024 and the potential of the AI-Immunology™ platform to address bacterial diseases. Petro Terblanche, CEO of Afrigen Biologics, highlighted the importance of developing effective interventions against gonorrhea, especially as antimicrobial resistance becomes a growing global challenge.


Gonorrhea, identified by the US Centers for Disease Control and Prevention (CDC) as one of the world's top five urgent antibiotic resistance threats, can lead to severe health complications and increase the risk of HIV transmission. The CDC estimates that there are 1.14 million new gonorrhea infections annually in the United States, with direct medical costs of approximately $133.4 million.


The findings from Evaxion's collaboration with Afrigen Biologics are based on a press release statement and provide a glimpse into the potential future of vaccine development, particularly for diseases with high unmet medical needs like gonorrhea.


In other recent news, Evaxion Biotech, an AI-driven biotechnology company, reported Q2 results with notable progress in its EVX-01 program. The company announced positive immune responses from its Phase 2 study of EVX-01 and improvements to its AI immunology platform. Despite global market uncertainties, Evaxion is hopeful about generating $14 million in business development income with current cash reserves expected to fund operations until early 2025.


New VP of Investor Relations and Communication, Mads Kronborg, was introduced by CEO Christian Kanstrup. The company's strategy emphasizes multi-partner collaborations and the pursuit of key milestones. Evaxion is engaged in partnership discussions in the areas of cancer and infectious diseases, with a focus on advancing these partnerships.


These developments are part of recent events at Evaxion Biotech. The company's optimism extends to the potential of its AI immunology platform and its EVX-01 cancer vaccine program. While acknowledging the uncertainties involved, Evaxion is committed to achieving significant business development income and maintaining cost optimization.


InvestingPro Insights


As Evaxion Biotech A/S (NASDAQ: EVAX) makes strides in vaccine development with its latest pre-clinical results for EVX-B2, a closer look at the company's financial health and market performance through InvestingPro provides key insights. Despite the promising scientific advancements, InvestingPro Tips indicate that analysts have concerns about the company's profitability, noting that Evaxion is not expected to be profitable this year and is quickly burning through cash. These considerations are crucial for investors who are evaluating the long-term viability of the company alongside its scientific potential.


InvestingPro Data reveals a market capitalization of $19.24 million, suggesting a relatively small player in the biotech industry. The company's price/book ratio, a measure of market valuation, stands at a high 15.35 as of the last twelve months ending Q2 2024. This could indicate that the stock is priced optimistically relative to the company's book value. Additionally, Evaxion has experienced a significant return over the last week, with a 13.11% price total return, and an even stronger performance over the past month, at 35.07%. This recent market activity may reflect investor reactions to the latest developments and suggests a potential trend of interest in the company's stock.


For investors intrigued by Evaxion's technological advancements and market movements, there are additional InvestingPro Tips available that provide deeper analysis and forecasts. These tips, which could further inform investment decisions, are accessible through the comprehensive InvestingPro platform.


As Evaxion navigates the challenges of bringing new vaccines to market, these financial metrics and expert insights offer a broader context for understanding the company's position within the competitive biotech landscape.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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