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Charles River teams up with CEBINA for neurodegeneration

Published 17/09/2024, 13:14
CRL
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WILMINGTON, Mass. & VIENNA - Charles River Laboratories International, Inc. (NYSE: CRL) and CEBINA GmbH announced today a strategic collaboration to advance the DanubeNeuro program, which aims to accelerate the development of new treatments for neurodegenerative diseases. The partnership will leverage Charles River's expertise in drug discovery and CEBINA's experience in biotech acceleration to foster innovation in addressing conditions such as Alzheimer's and Parkinson's disease.


The DanubeNeuro program is designed to identify and develop novel academic research projects that could lead to innovative drugs, diagnostic methods, biomarkers, and imaging techniques for neurodegenerative diseases. Charles River and CEBINA's combined efforts will focus on enhancing the program's ability to speed up the innovation process in the field of neurodegeneration.


Aidan Synnott, PhD, Corporate Vice President, Global Discovery (NASDAQ:WBD) Services at Charles River, emphasized the company's commitment to scientific research and expressed eagerness to contribute their expertise to the acceleration program.


As populations age globally, neurodegenerative disorders are becoming increasingly prevalent and represent significant medical and societal challenges. The collaboration between Charles River and CEBINA is expected to aid in the transition of academic research into potential drug development programs, addressing the urgent need for new strategies to combat these complex diseases.


Eszter Nagy, MD, PhD, CEO&CSO of CEBINA, highlighted the importance of Charles River's role in the selection and development of product candidates, believing that their expertise will de-risk the investment process and help achieve the goal of improving patient lives.


The DanubeNeuro initiative, which started four months ago, has been supported by the dedicated fund, Danube BioVentures, and has already seen a promising influx of innovative academic research proposals. With a rolling application process, the program continues to seek submissions from researchers looking to make an impact in the area of neurodegeneration.


This collaboration is based on a press release statement and represents a factual summary of the strategic partnership between Charles River Laboratories International, Inc. and CEBINA GmbH within the DanubeNeuro program.


In other recent news, Charles River Laboratories reported a 3.2% decrease in its second-quarter revenue to $1.03 billion, mainly due to lower sales in the Discovery Services and Safety Assessment (DSA) segments. In response, the company has implemented cost-saving measures and initiated a $1 billion stock repurchase program. Charles River has also revised its full-year revenue outlook, projecting a 3% to 5% organic decline. Analyst firms including Mizuho Securities, TD Cowen, JPMorgan (NYSE:JPM), and Baird have adjusted their outlooks on Charles River, citing concerns about the DSA segment and weaker demand.


In a strategic move, Charles River has announced a five-year collaboration with Insightec to enhance drug discovery and preclinical development in neuroscience. The partnership aims to leverage Insightec's non-invasive low-frequency ultrasound platform to improve neurological drug delivery.


Despite the challenges, Charles River Labs (NYSE:CRL) reiterated its guidance in the Research Models and Services (RMS) segment and slightly increased projections in its Manufacturing support area. These developments are seen as minor positive developments amidst the broader industry challenges.


InvestingPro Insights


As Charles River Laboratories International, Inc. (NYSE: CRL) embarks on a strategic collaboration with CEBINA GmbH to advance treatments for neurodegenerative diseases, understanding the company's financial health becomes crucial for investors monitoring the potential impact of such partnerships. According to InvestingPro data, Charles River's market capitalization stands at a robust $10.52 billion, reflecting investor confidence in the company's market position. Despite facing a slight revenue decline of -2.41% over the last twelve months as of Q2 2024, the company maintains a strong gross profit margin of 35.98%, showcasing its ability to manage costs effectively in a challenging environment.


From an investment perspective, Charles River's P/E ratio, a measure of a company's current share price relative to its per-share earnings, is 24.26, with a slight increase to 25.7 when adjusted for the last twelve months as of Q2 2024. This indicates that investors are willing to pay a higher price for earnings, possibly due to expectations of future growth. Notably, InvestingPro Tips highlight that analysts predict the company will be profitable this year and that it has been profitable over the last twelve months. Additionally, Charles River does not pay a dividend, which could suggest a reinvestment of earnings back into the company for further research and development—critical for a company deeply involved in drug discovery for neurodegenerative diseases.


Investors interested in further insights and detailed analysis can find additional InvestingPro Tips on Charles River Laboratories International, Inc. at InvestingPro, with 15 analysts having revised their earnings downwards for the upcoming period, indicating the importance of keeping abreast of market sentiment and future earnings projections.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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