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ArriVent and Alphamab enter $615.5 million cancer drug pact

EditorNatashya Angelica
Published 05/06/2024, 17:10
AVBP
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SUZHOU, China and NEWTOWN SQUARE, Pa. - ArriVent BioPharma, Inc., a clinical-stage biopharmaceutical company, has announced a collaboration with Jiangsu Alphamab Biopharmaceuticals Co., Ltd., a subsidiary of Alphamab Oncology, focused on the discovery, development, and commercialization of novel antibody drug conjugates (ADCs) for cancer treatment. This partnership is expected to strengthen ArriVent's pipeline by potentially adding new ADC programs.

Under the terms of the agreement, ArriVent has secured exclusive rights to develop and commercialize ADCs globally, with the exception of greater China, where Alphamab retains rights. The deal includes an upfront and potential milestone payments totaling up to $615.5 million, along with tiered sales royalties for each ADC product sold by ArriVent.

Both companies will utilize Alphamab's proprietary linker-payload platform and glycan-conjugation technology to identify novel ADCs. Alphamab's Chairman and CEO, Ting Xu, Ph.D., expressed enthusiasm for the partnership, highlighting the synergy between Alphamab's research and discovery capabilities and ArriVent's oncology expertise.

ArriVent is dedicated to the development and commercialization of innovative therapeutics for cancer patients, with a focus on maximizing the potential of its lead development candidate, firmonertinib, and advancing a pipeline of novel therapeutics, including next-generation ADCs.

Alphamab Oncology is recognized as a leader in biopharmaceuticals in China, with a robust pipeline of monoclonal antibodies, bispecific antibodies, and antibody-drug conjugates, including one approved for marketing in China and three in late clinical stages.

The collaboration is based on shared goals of addressing the unmet medical needs of cancer patients and delivering impactful oncology therapeutics. The information in this article is based on a press release statement.

In other recent news, ArriVent BioPharma has announced the addition of Kristine Peterson to its Board of Directors. Peterson brings over three decades of experience in the pharmaceutical industry, including significant roles at Valeritas, Inc., Johnson & Johnson, Biovail Corporation, and Bristol-Myers Squibb Company (NYSE:BMY).

She has also been active in governance roles, serving on boards of several pharmaceutical companies and advisory positions with the Healthcare Businesswomen’s Association and the Biotechnology Industry Organization (BIO) Board.

ArriVent BioPharma's Board has confirmed that Peterson qualifies as an independent director under the Nasdaq Stock Market’s governance listing standards. There are no undisclosed arrangements or conflicts of interest concerning her appointment.

Peterson's role and potential committee assignments are yet to be determined. This recent development is expected to bring valuable insight and leadership to ArriVent BioPharma as it continues to navigate the pharmaceutical landscape.

InvestingPro Insights

Amidst the strategic collaboration between ArriVent BioPharma and Jiangsu Alphamab Biopharmaceuticals, investors are closely monitoring ArriVent's financial health and market position. According to real-time data from InvestingPro, ArriVent BioPharma, Inc. (AVBP) currently holds a market capitalization of $613.94 million.

Despite the potential for future growth through the ADC programs, the company's financial metrics reflect some challenges. The P/E Ratio stands at -1.92, indicating that the company is not generating a profit relative to its share price. Furthermore, the adjusted P/E Ratio for the last twelve months as of Q1 2024 is even lower at -8.23, reinforcing concerns about profitability.

InvestingPro Tips reveal critical insights into ArriVent's financial situation. The company maintains more cash than debt, suggesting a solid liquidity position, with liquid assets surpassing short-term obligations. This is particularly important as it ensures that ArriVent has the financial flexibility to invest in its ADC collaboration and other research endeavors.

Still, ArriVent suffers from weak gross profit margins and analysts do not anticipate the company will be profitable this year. Moreover, the company did not turn a profit over the last twelve months and does not pay a dividend to shareholders, which might be a concern for income-focused investors.

For those considering an investment in ArriVent or seeking to understand the company's financial standing in light of this new partnership, InvestingPro offers additional insights. There are 5 more InvestingPro Tips available, which could provide further guidance on the investment potential of AVBP. Interested readers can explore these tips and benefit from a special offer: use coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription at InvestingPro. With these tools, investors can make more informed decisions aligned with their investment strategies.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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