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Aligos reports positive Phase 1 data for coronavirus drug

EditorNatashya Angelica
Published 25/04/2024, 21:18
ALGS
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SOUTH SAN FRANCISCO - Aligos Therapeutics, Inc. (NASDAQ:ALGS), a biopharmaceutical company, announced positive Phase 1 results for its investigational drug ALG-097558, a pan-coronavirus protease inhibitor, at the 34th European Society of Clinical Microbiology and Infectious Diseases (ESCMID) 2024 on April 28.

The company, which focuses on developing therapies for liver and viral diseases, revealed that the drug was well tolerated in healthy volunteers. The study tested single doses up to 2000 mg and multiple doses up to 800 mg every 12 hours for seven days. According to the data, ALG-097558 has a pharmacokinetic profile that supports twice-daily dosing without the need for ritonavir boosting or food intake considerations.

Lawrence Blatt, Ph.D., MBA, Chairman, President, and CEO of Aligos Therapeutics, stated, "These data further highlight the best-in-class potential of this pan-coronavirus protease inhibitor and its substantial differentiation versus current standard of care coronavirus antiviral drugs like nirmatrelvir/ritonavir (PAXLOVID™)."

The company is optimistic about the drug's potential and is planning to continue its development with the support of various external funding sources, including government agencies. The development is part of Aligos's broader clinical pipeline, which includes three drug candidates aimed at addressing unmet medical needs.

Aligos Therapeutics was founded in 2018 and has since been working on therapeutics for conditions such as metabolic dysfunction-associated steatohepatitis (MASH), hepatitis B, and coronaviruses.

The Phase 1 data presented at ESCMID 2024 is based on a press release statement from Aligos Therapeutics. The company's forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from those anticipated.

These include challenges in drug development, clinical trials, regulatory approval processes, manufacturing, intellectual property protection, and the impact of global events on business operations.

InvestingPro Insights

Following the recent announcement by Aligos Therapeutics (NASDAQ:ALGS) of their positive Phase 1 results for ALG-097558, a look at the company's financial health and stock performance provides additional context for investors. Aligos Therapeutics currently holds a market capitalization of $61.9 million, reflecting its status as a smaller biopharmaceutical player in the industry.

An important metric for investors to consider is the company's revenue growth. Aligos has reported an 11.66% increase in revenue over the last twelve months as of Q4 2023. This indicates a growing interest in the company's product pipeline, despite a quarterly revenue decline of 24.2% in Q4 2023. The company's gross profit margin stands at a negative 370.35%, underscoring challenges in achieving profitability.

Investors should note that Aligos's stock price has experienced significant volatility, with a strong return of 18.43% over the last three months and an even larger uptick of 34.88% over the past six months. This could be indicative of market optimism about the company's pipeline potential, despite the fact that analysts do not expect Aligos to be profitable this year.

Two InvestingPro Tips for Aligos Therapeutics highlight the company's financial position and market performance. Firstly, Aligos holds more cash than debt on its balance sheet, which is a positive sign for its financial stability.

Secondly, the company's stock price movements have been quite volatile, which is a factor for investors to consider when evaluating risk. For those interested in a deeper analysis, there are 10 additional InvestingPro Tips available for Aligos Therapeutics at https://www.investing.com/pro/ALGS, which can provide further insights into the company's valuation and market prospects.

For investors looking to leverage these insights into their investment strategy, InvestingPro offers a wealth of data and analytics. Make sure to use the coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription, unlocking access to a comprehensive suite of investment tools and expert analysis.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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