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Sanofi Taps Adagene's 'Masking' Tech In Over $2.5B Immuno-Oncology Pact

Published 02/03/2022, 14:55
Updated 02/03/2022, 15:40
© Reuters.  Sanofi Taps Adagene's 'Masking' Tech In Over $2.5B Immuno-Oncology Pact

  • Sanofi (PA:SASY) SA (NASDAQ: SNY) has signed a collaboration with Adagene Inc (NASDAQ: ADAG) to advance two preclinical immuno-oncology candidates and an option to develop two more.
  • Sanofi is paying $17.5 million upfront and promising up to $2.5 billion in potential milestones.
  • Under the terms of the agreement, Adagene will be responsible for early-stage research activities to develop masked versions of Sanofi candidate antibodies using Adagene's SAFEbody technology.
  • Also See: Adagene's Posts Early Safety, Efficacy Data From Cold Tumors Trial.
  • Sanofi will be solely responsible for later-stage research and all clinical, product development, and commercialization activities.
  • SAFEbody technology uses precision masking to shield the binding domain of the biologic therapy. Activating the tumor microenvironment allows for tumor-specific targeting of antibodies while minimizing on-target off-tumor toxicity in healthy tissues.
  • Price Action: ADAG shares are up 8.36% at $5.96, while SNY stock is down 0.67% at $50.72 during the market session on the last check Wednesday.
© 2022 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

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